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Crizotinibの未加工粉の抗腫瘍性のMultitargetプロテアーゼ抑制剤877399-52-5

Crizotinibの未加工粉の抗腫瘍性のMultitargetプロテアーゼ抑制剤877399-52-5

    • Crizotinib Raw Powder Antineoplastic Multitarget Protease Inhibitors 877399-52-5
    • Crizotinib Raw Powder Antineoplastic Multitarget Protease Inhibitors 877399-52-5
  • Crizotinib Raw Powder Antineoplastic Multitarget Protease Inhibitors 877399-52-5

    商品の詳細:

    起源の場所: 中国
    ブランド名: FuLu
    証明: ISO9001
    モデル番号: 1421373-65-0

    お支払配送条件:

    最小注文数量: 交渉可能な
    価格: Negotiable
    パッケージの詳細: 1kg 保証される習慣パスのための生殖不能のアルミ ホイル袋または慎重で、堅く安全なパッキング
    受渡し時間: 支払の後の 24h の中では
    支払条件: ウェスタン・ユニオン、MoneyGram、T/Tのビット硬貨
    供給の能力: 多くの在庫
    接触
    詳細製品概要
    製品名: Crizotinib Fuction: 医薬中間体
    使用法: 抗腫瘍性 タイプ: 医薬品原料
    白色粉末: 白色粉末 CAS: 1421373-65-0
    ハイライト:

    active pharmaceutical ingredients

    ,

    raw material medicine

    Crizotinib Raw Powder Antineoplastic Multitarget Protease Inhibitors

     

    Basic infor

     

     

    Product name

    Crizotinib

    CAS

    877399-52-5

    MF

    C21H22Cl2FN5O

    MW

    450.343

    Purity

    99% min

    Appearance

    White Crystalline Powder

    MOQ

    10 grams

    Storage

    Store in a cool, dry place

    Deliver time

    About 5 days

    Deliver methods

    By express (door to door)

     

     

    What is Crizotinib

     


    Crizotinib (trade name Xalkori,) is an anti-cancer drug acting as an ALK (anaplastic lymphoma kinase) and ROS1 (c-ros oncogene 1) inhibitor, approved for treatment of some non-small cell lung carcinoma (NSCLC) in the US and some other countries, and undergoing clinical trials testing its safety and efficacy inanaplastic large cell lymphoma, neuroblastoma, and other advanced solid tumors in both adults and children.

     

     

    How does Crizotinib works
     


    Crizotinib has an aminopyridine structure, and functions as a protein kinase inhibitor by competitive binding within the ATP-binding pocket of target kinases. About 4% of patients with non-small cell lung carcinoma have a chromosomal rearrangement that generates a fusion genebetween EML4 ('echinoderm microtubule-associated protein-like 4') andALK ('anaplastic lymphoma kinase'), which results in constitutivekinase activity that contributes to carcinogenesis and seems to drive the malignant phenotype. The kinase activity of the fusion protein is inhibited by crizotinib. Patients with this gene fusion are typically younger non-smokers who do not have mutations in either theepidermal growth factor receptor gene (EGFR) or in the K-Ras gene.The number of new cases of ALK-fusion NSLC is about 9,000 per year in the U.S. and about 45,000 worldwide.

     

     

    COA

     

     

    Test Items

    Specification

    Results

    Description

    White to off white crystalline powder

    Comply

    Melting point

    166-170ºC

    167.3-168.1ºC

    Identification

    Positive reaction

    Positive reaction

    Related substances

    <1.0%

    0.16%

    Loss on drying

    <0.5%

    0.06%

    Residue on ignition

    <0.1%

    0.02%

    Chloride

    <0.014%

    <0.014

    Heavy Metals

    <20ppm

    <20ppm

    Clarity of solution

    Conform to standard

    Complies

    Microbial Limit

    <20ppm

    <20ppm

    Assay

    >99.0%

    99.12%

     

     

    High quality with competitive price

     

     

    1)Tell the package update ASAP , and will try best solve when customer encountered various problems.

    2)we will teach you recipes and instructions for all kind of steroid to turn powder into liquid , and liquid become sterile ones.


    We have clients throughout the world

     

     

    1)Professional service and rich experience make customers feel comfortable and trust us.

    2)Adequate stock(such as Anti Estrogen Steroids) and fast delivery meet their demand.

    3)Market feedback and products feedback will be appreciated, meeting customers's requirement is our responsibility.

    4) High quality and competitive price gain the trust and praise from the customers around the world.


    Fast and safe delivery

     

     

    1)Parcel can be sent out in 24 hours after comfirming payment.

    2) Various transportation methods for your choice , such as EMS , FedEx , TNT , DHL , USP.

    3) We have our own agent who can help us ship our products fastly and safely , and we have enough stock in there for transferring.

    4)We have special way could ship 10g to sveral kg products a time. We offer melting powder into liquid service. And ship the liquid in special package ways.

    5)Offer the latest tracking number for you to check.

     

     


    Flexible Payment term

     


    We accept every payment term , such as T/T , Bitcoin , Moneygram , .

    High quality with competitive price
    We are manufacturer and can provide high quality products with competitive price , offering free samples totest , a few shipping fee only.

     

     

    Crizotinibの未加工粉の抗腫瘍性のMultitargetプロテアーゼ抑制剤877399-52-5

     

     

     

    連絡先の詳細
    SuZhou FuLu Biotech Co.,Ltd

    コンタクトパーソン: Jessie

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